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簡(jiǎn)要描述：Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
產(chǎn)品型號(hào)：bsm-61302R廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2025-02-28訪 問(wèn) 量： 117產(chǎn)品分類
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