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簡(jiǎn)要描述：Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1). CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irrad
產(chǎn)品型號(hào)：bsm-61709R廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2025-03-01訪 問(wèn) 量： 113產(chǎn)品分類(lèi)
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